Cardiac remodeling in obesity

Abstract

We have reviewed data concerning cardiac structure and function. We believe that the following conclusions are justified by the data available. Cardiac remodeling in obesity is characterized by concentric geometry at least as often as eccentric geometry (Figure 7). Most, but not all studies also demonstrate subtle, likely subclinical, abnormalities in myocardial function and diastolic filling, some of which are reversible with weight loss. Given the prevalence of obesity, the frequency of these subtle findings is not only of academic interest. If LV remodeling precedes preclinical systolic dysfunction, identification of structural and functional abnormalities might allow us to certain patients for special counseling regarding weight loss, by pointing out that they already have evidence of heart disease. © 2013 American Heart Association, Inc.