The efficacy and safety of acupuncture for perimenopausal insomnia: A protocol for a network meta-analysis

Abstract

Background: As a common symptom of perimenopausal period, perimenopausal insomnia brings great pain to many women and families. Acupuncture has been accepted by people as the incidence rate of this disease increases. The purpose of this study is to systematically compare the safety and efficacy of various acupuncture treatments for perimenopausal insomnia through network meta-analysis. Methods: We will search Web of Science, PubMed, The Cochrane Library, Embase, Chinese National Knowledge Infrastructure (CNKI), Wan Fang Date, VIP database, conference papers and grey literature. All relevant Randomized controlled trial (RCT) using acupuncture for perimenopausal insomnia will be included. Two reviewers will independently search and screen date. Network metaanalysis will be completed by Stata and WinBUGS software. Results: This study will compare the efficacy and safety of different acupuncture treatments for perimenopausal insomnia. Conclusion: The result of this study will provide reliable evidence for evaluating the efficacy and safety of acupuncture in the treatment of perimenpausal insomnia. INPLASY registration number: INPLASY2020110047. Abbreviations: CL = confidence interval, CNKI = Chinese National Knowledge Infrastructure, GRADE = Grading of Recommendations Assessment, Development and Evaluation, HRT = hormone replacement therapy, MD = mean different, MeSH = Medical Subject Heading, NMA = network meta-analysis, OR = odds rations, PSQI = Pittsburgh Sleep Quality Index Scale, RCT = randomized controlled trial, SF-36 = Quality of Life Scale, SUCRA = surface under the cumulative ranking area.