Abstract
Eupenifeldin was isolated from cultures of Eupenicillium brefeldianum ATCC 74184 by extraction and crystallization. The compound was identified as a pentacyclic bistropolone on the basis of spectral data and its complete structure was established by single-crystal X-ray analysis. The compound is cytotoxic against the HCT-116 cell line and has in vivo antitumor activity in the P388 leukemia model. © 1993, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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CITATION STYLE
Mayerl, F., Gao, Q., Huang, S., Klohr, S. E., Matson, J. A., Gustavson, D. R., … Rose, W. C. (1993). Eupenifeldin, a novel cytotoxic bistropolone from eupen icillium brefeldianum. Journal of Antibiotics, 46(7), 1082–1088. https://doi.org/10.7164/antibiotics.46.1082
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