Two-years results of small-incision lenticule extraction and wavefront-guided laser in situ keratomileusis for Myopia

Abstract

Purpose: To compare the 2-years visual and refractive outcomes between small-incision lenticule extraction (SMILE) and wavefront-guided laser in situ keratomileusis (LASIK) in eyes with myopia and myopic astigmatism. Methods: Our retrospective case–control study examined 30 eyes of 30 patients with the manifest refraction spherical equivalent (MRSE) of −3.71 ± 1.83 dioptres (D) who underwent SMILE and 30 eyes of 30 patients with MRSE of −3.81 ± 1.40 D who underwent wavefront-guided LASIK. We assessed the 2-years clinical outcomes. Results: Logarithm of the minimal angle of resolution (LogMAR)-corrected distance visual acuity (CDVA) was −0.23 ± 0.07 in the SMILE group and −0.24 ± 0.07 in the wavefront-guided LASIK group 2 years postoperatively (p = 0.82). Logarithm of the minimal angle of resolution-uncorrected distance visual acuity (UDVA) was −0.18 ± 0.09 and −0.15 ± 0.11 (p = 0.30, respectively). In the SMILE and wavefront-guided LASIK groups 2 years postoperatively, 100% and 73% of eyes, respectively, were within 0.5 D of the prompted MRSE correction (p = 0.005). Changes in the MRSE of −0.10 ± 0.30 D and −0.23 ± 0.51 D occurred from 3 months to 2 years (p = 0.40, respectively). We found a significant correlation between myopic regression and the changes in the keratometric readings from 3 months to 2 years after wavefront-guided LASIK (r = −0.48, p = 0.002), but not after SMILE (r = −0.004, p = 0.90). Conclusion: Small-incision lenticule extraction offers better refractive outcomes than wavefront-guided LASIK during a 2-years follow-up for the correction of myopia and myopic astigmatism.