Investigation of the pharmacological properties and antioxidant activity of Curcuma Longa.L

Abstract

The current work was carrying out to quantifie the total phenolic, flavonoids also proanthocyanidins contents. The phytochemicals, GC-MS analysis antioxidant and antibacterial activity of Curcuma rhizomes extracts, and they were evaluated using standard methods of determination of Phenolic contents, antioxidant, and antibacterial activity. The extracts were obtained by Ultrasonic-assisted extraction (UAE), the quantification of polyphenolic, flavonoids and proanthocyanidins contents presented a important value regarding the ethanolic extract (15.3g GAE/100g), (8.5 g CE/100g), (20.31 g TE/100g), respectively, also the antimicrobial inhibitory effect showed a remarkable activity, in addition GC-MS analysis of the extracts exposed the existence of indole, phytol and other important compounds of interest and showed better radical scavenging activity than the control in this study. Most of the phytochemicals present and some of the compounds revealed by GC-MS analysis, which are biologically active with physiological activities, could be the source of the antioxidant and antibacterial activity of the sample. They might as well be responsible for the pharmacological propreties derived from our samples. This study revealed the pharmacological importance, antimicrobial and antioxidant inhibitory potential of the extracts of Curcuma longa.L.