Abstract
The cyclic lipopeptide Daptomycin, used as a treatment for infections where antimicrobial resistance is observed, is shown to self-assemble into spherical micelles above a critical aggregation concentration. Micelles are observed either in the absence or presence of CaCl2 , in contrast to claims in the literature that CaCl2 is required for micellization.
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Kirkham, S., Castelletto, V., Hamley, I. W., Inoue, K., Rambo, R., Reza, M., & Ruokolainen, J. (2016). Self-Assembly of the Cyclic Lipopeptide Daptomycin: Spherical Micelle Formation Does Not Depend on the Presence of Calcium Chloride. Chemphyschem : A European Journal of Chemical Physics and Physical Chemistry, 17(14), 2118–2122. https://doi.org/10.1002/cphc.201600308
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