Review Artikel: Penggunaan Lipid Asam Stearat Dalam Sistem Penghantaran Obat Berbasis Nanopartikel

Abstract

The pharmaceutical formulation continues to be developed in order to obtain maximum therapeutic effects with minimal side effects. The increasing use of nanoparticles in pharmaceutical products is based on the fact that the preparations manufactured with the nanoparticle system have an advantage such as active substances, which are selective and effectively meet up with the targeted site and the active substances, which are released in order to control and minimize any adverse side effects. Furthermore, literature searches were carried out using online-based library search tools, such as Google Scholar, NCBI-PubMed and ELSEVIER for a total of 50 articles. The use of stearic acid as a nanoparticles matrix are used as a carrier for lipophilic active substances and are able to control the active substances release. This research provides information on the use of stearic acid lipids in various nanoparticle preparations.