Enhancing brain lesions after endovascular treatment of aneurysms

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Abstract

Complications of endovascular therapy of aneurysms mainly include aneurysm rupture and thromboembolic events. The widespread use of MR imaging for follow-up of these patients revealed various nonvascular complications such as aseptic meningitis, hydrocephalus, and perianeurysmal brain edema. We present 7 patients from 5 different institutions that developed MR imaging- enhancing brain lesions after endovascular therapy of aneurysms, detected after a median time of 63 days. The number of lesions ranged from 4-46 (median of 10.5), sized 2-20 mm, and were mostly in the same vascular territory used for access. Three patients presented with symptoms attributable to these lesions. After a median follow-up of 21.5 months, the number of lesions increased in 2, was stable in 1, decreased in 3, and disappeared in 1. The imaging and clinical characteristics suggested a foreign body reaction. We could find no correlation to a specific device, but a possible source may be the generic hydrophilic coating.

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Cruz, J. P., Marotta, T., O’Kelly, C., Holtmannspötter, M., Saliou, G., Willinsky, R., … Agid, R. (2014). Enhancing brain lesions after endovascular treatment of aneurysms. American Journal of Neuroradiology, 35(10), 1954–1958. https://doi.org/10.3174/ajnr.A3976

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