Erhöhte Prävalenz konnataler Tränenwegsstenosen nach Sectio caesarea

Abstract

Background: Congenital nasolacrimal duct obstruction (dacryostenosis) with a persisting membrane at Hasnerʼs valve is the most common cause of persistent tear and ocular discharge in infants. Purpose: To evaluate whether there is an association between congenital dacryostenosis and delivery via cesarean section. Material and methods: In a prospective study we examined 107 children (mean age 9.2 ± 7.1 months) with congenital dacryostenosis. We evaluated data about the mode of delivery (vaginal delivery versus cesarean section) and gestational age at the time of birth. Within the first 8 months of life children were treated by probing using local anesthesia, whereas older children were treated using general anesthesia. After the age of 11 months treatment included nasolacrimal duct intubation with a bicanalicular stent. Statistical analyses were performed using binomial tests, Fisherʼs exact test and the t-test. Results: In this study 51 children delivered by cesarean section were compared with 56 children delivered by spontaneous vaginal delivery. A total of 44 age-matched pairs from both groups were evaluated in order to eliminate confounding factors due to gestational age at delivery. Based on the published rate of cesarean sections from the same region of the State of Hesse between 2002–2004 we observed a statistically significant association between congenital dacryostenosis and delivery by cesarean section among the 88 age-matched patients (P = 0.009). Moreover, subgroup analysis revealed a significant association between congenital dacryostenosis and delivery by primary cesarean section (P = 0.00004). The prevalence of surgical treatment was not statistically different between both groups based on the mode of delivery (P = 0.8). Conclusion: Our results suggest that delivery via cesarean section is associated with a significantly higher prevalence of congenital dacryostenosis.