Congenital toxoplasmosis

Abstract

The aim of study was to make an overview of clinical signs caused by congenital toxoplasmosis and methods of diagnosis in Budapest, Hungary. The most frequent sign of congenital infection among our patients were cerebral ultrasonographic changes (calcification, hydrocephalus, microcephaly), neurologic disturbances (muscle tone disturbances, seizures) and chorioretinitis. We observed hepatic failure rarely. The differencial diagnosis of ultrasonographic changes included as other causes of hydrocephalus (hemorrhage, CMV or other infections) as other causes of calcification (CMV or other infections) too. The differential diagnosis of eye lesions included colobomatous defect, other inflammatory lesions (HSV, CMV), birth injury (intraocular hemorrhage) circulatory disturbances or neoplasm.