Development and validation of a nomogram for predicting early stress urinary incontinence following endoscopic enucleation of the prostate

Abstract

Purpose: To develop and validate a predictive nomogram for early stress urinary incontinence (SUI) after endoscopic enucleation of the prostate (EEP) in patients with benign prostatic hyperplasia (BPH). Methods: The records of 458 patients who underwent plasmakinetic- or diode-based EEP at our center from March 2016 to December 2019 were reviewed. Among these, 326 and 132 cases were randomly assigned to the training and validation set, respectively. A predictive nomogram was constructed based on multivariate logistic regression analysis. Receiver operating characteristic (ROC) analysis and calibration curves were employed to evaluate its performance. Results: 65 years ≤ age < 70 years, 75 years ≤ age, 25 kg/m2 ≤ BMI < 30 kg/m2, 30 kg/m2 ≤ BMI, 5 years ≤ LUTS duration, and 75 ml ≤ prostate volume were finally selected as independent predictors of early SUI into the multivariate logistics regression model. It was visualized as a concise nomogram with satisfactory discrimination and accuracy in both training and validation sets. Conclusions: A concise nomogram was developed and validated as a useful clinical tool for predicting early SUI post-EEP.