Discovering the Cause of Wiskott–Aldrich Syndrome and Laying the Foundation for Understanding Immune Cell Structuring

Abstract

The discovery of the Wiskott–Aldrich syndrome (WAS) protein gene ( WASP , now known as WAS ) by Derry et al. ([1][1]) in 1994 accelerated the field of immune cell biology and studies of the molecular basis of inborn human immune defects, otherwise known as primary immunodeficiencies (PIDs). It was