Co-circulation of Plasmodium vivax and Arboviruses in the Brazil–French Guiana Border

Abstract

Background: Co-circulation of Plasmodium vivax and arboviruses is a significant but underexplored public health concern in tropical regions. Methods: We analyzed 300 serum samples collected between 2014 and 2015 from the Brazil–French Guiana border, including 102 malaria cases and 198 controls, using rapid tests for Immunoglobulin M (IgM), Immunoglobulin G (IgG), and Non-Structural Protein 1 (NS1). Results: High IgG reactivity for dengue and chikungunya viruses was observed. Co-reactivity was frequent. Zika virus detection was minimal. Conclusions: The overlapping transmission of P. vivax and arboviruses highlights the need for integrated surveillance strategies to better address co-circulation/co-infection risks.