A Function for Subtelomeric DNA in Saccharomyces cerevisiae

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Abstract

The subtelomeric DNA sequences from chromosome I of Saccharomyces cerevisiae are shown to be inherently poor substrates for meiotic recombination. On the basis of these results and prior observations that crossovers near telomeres do not promote efficient meiosis I segregation, we suggest that subtelomeric sequences evolved to prevent recombination from occurring where it cannot promote efficient segregation.

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Barton, A. B., Su, Y., Lamb, J., Barber, D., & Kaback, D. B. (2003). A Function for Subtelomeric DNA in Saccharomyces cerevisiae. Genetics, 165(2), 929–934. https://doi.org/10.1093/genetics/165.2.929

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