CADNet157 model: fine-tuned ResNet152 model for breast cancer diagnosis from mammography images

Abstract

The risk of death incurred by breast cancer is rising exponentially, especially among women. This made the early breast cancer detection a crucial problem. In this paper, we propose a computer-aided diagnosis (CAD) system, called CADNet157, for mammography breast cancer based on transfer learning and fine-tuning of well-known deep learning models. Firstly, we applied hand-crafted features-based learning model using four extractors (local binary pattern, gray-level co-occurrence matrix, and Gabor) with four selected machine learning classifiers (K-nearest neighbors, support vector machine, random forests, and artificial neural networks). Then, we performed some modifications on the Basic CNN model and fine-tuned three pre-trained deep learning models: VGGNet16, InceptionResNetV2, and ResNet152. Finally, we conducted a set of experiments using two benchmark datasets: Digital Database for Screening Mammography (DDSM) and INbreast. The results of the conducted experiments showed that for the hand-crafted features based CAD system, we achieved an area under the ROC curve (AUC) of 95.28% for DDSM using random forest and 98.10% for INbreast using support vector machine with the histogram of oriented gradients extractor. On the other hand, CADNet157 model (i.e., fine-tuned ResNet152) was the best performing deep model with an AUC of 98.90% (sensitivity: 97.72%, specificity: 100%), and 98.10% (sensitivity: 100%, specificity: 96.15%) for, respectively, DDSM and INbreast. The CADNet157 model overcomes the limitations of traditional CAD systems by providing an early detection of breast cancer and reducing the risk of false diagnosis.