Preparation of mesoporous SBA-16 silica-supported biscinchona alkaloid ligand for the asymmetric dihydroxylation of olefins

Abstract

Optically active cinchona alkaloid was anchored onto mesoporous SBA-16 silica and the as-prepared complex was used as a heterogeneous chiral ligand of osmium tetraoxide for the asymmetric dihydroxylation of olefins. The prepared catalytic system provided 90-93% yield of vicinal diol with 92-99% enantioselectivity. The ordered mesoporous SBA-16 silica was found to be a valuable support for the cinchona alkaloid liganded osmium catalyst system which is frequently used in chemical industries and research laboratories for olefin functionalization. © 2014 Shaheen M. Sarkar et al.