Treatment of ACS in Diabetic Patients in Non-invasive versus Invasive hospitals of Saudi Arabia, A Prospect from MIDAS Registry

Abstract

Background and Purpose: In the setting of unstable angina/non-ST-segment elevation acute coronary syndromes (UA/NSTEMI- ACS), diabetes mellitus particularly were found to be an independent predictor of mortality. We present the treatment trends of NSTEMI- ACS in diabetic patients in King Abdulaziz Medical city National Guard Hospital (KAMC) in Jeddah in comparison to the whole Kingdom of Saudi Arabia (KSA). Data are derived from the results of Multicenter International Diabetes - Acute Coronary Syndromes (MIDAS) study. Design: Diabetic patients presenting with UA/NSTEMI- ACS where enrolled into the study at the time of admission to the emergency/coronary care department. A total of 3624 patients were enrolled in several countries; 35 from KAMCamong total of 142 from KSA. Results: The patients enrolled were 94% type 2 DM in KSA, while in Jeddah,the percentage was 100% and theyhad more prevalent high risk factors. Glycoprotein IIb/IIIa inhibitors were more utilized appropriately in Jeddah, particularly in the elderly, in comparison to thewholeKSA,but less than the recommended guidelines. While the use of Clopedogril / Ticlopidine was similarly high in both populations. Conclusions: The non-invasive approach did not affect the trends of treatment in KAMC. GP IIb/IIIa inhibitors are underutilized in KAMC; however it was more utilized than the whole KSA. Clopedogril / Ticlopidineuse were optimal in both location. (Figure Presented).