Rhinocerebral mucormycosis

Abstract

The purpose of this presentation is to describe a fatal outcome of a diabetic patient with rhinocerebral mucormycosis. The natural disease process in uncontrolled diabetic and immunosuppressed patients is described. The disease process can spread rapidly intercrainally from the sinonasal tract via vascular channels, orbital invasion or direct extension through the cribiform plate. Infarction, necrosis, and Cavernous sinus thrombosis are lethal complications. Cat scan and MRI are critical in early detection. Biopsy of suspicious tissue is essential. Early management of the predisposing disorder, administration of Amphotericin B, and aggressive surgical intervention should be initiated early are essential measures in order to reverse the fatal outcome of patients with mucormycosis.