Treatment of transmissible venereal tumor without metastasis in mixed local Balinese dog by surgery and vincristine sulfate: A case report

Abstract

A three-year-old mixed local Balinese female dog with 8.8 weight was examined with a mass and swelling in the vaginal area accompanied by blood discharge. Based on histopathological findings, the animal was diagnosed with a transmissible venereal tumor. After physical examination and radiographic evaluation, it can be concluded that there is no metastasis. Treatment is carried out by surgery to excise the tumor mass and followed by chemotherapy using vincristine sulfate at a dose of 0.025 mg/kg BW three times at intervals of seven days. Hematological examination before treatment showed lymphocytosis and microcytic hypochromic anemia, and after treatment showed microcytic hypochromic anemia without lymphocytosis. After surgery, the animals were given cefotaxime antibiotic intravenously for two days and continued with cefixime orally for five days. Mefenamic acid analgesia was given for three days orally. On the seventh day after surgery, the wound healed clinically. After two months of follow-up, there were no signs of tumor recurrence. Treatment with surgery and chemotherapy has been shown to be effective in treating TVT case without metastasis.