Quantitative measurements of proton spin-lattice (T1) and spin-spin (T2) relaxation times in the mouse brain at 7.0 T

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Abstract

The goal of this work is to provide regional T1 and T2 values at a field strength of 7 T for the normal mouse brain at 6 weeks and 1 year old. A novel segmented snapshot FLASH sequence was used to measure T1 in the hippocampus, corpus callosum, and the retrosplenial granular (RSG) cortex; T2 measurements were made in the same regions using a single spin echo sequence repeated at six separate echo times. Both T1 and T2 measurements were validated with phantom measurements. © 2003 Wiley-Liss, Inc.

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Guilfoyle, D. N., Dyakin, V. V., O’Shea, J., Pell, G. S., & Helpern, J. A. (2003). Quantitative measurements of proton spin-lattice (T1) and spin-spin (T2) relaxation times in the mouse brain at 7.0 T. Magnetic Resonance in Medicine, 49(3), 576–580. https://doi.org/10.1002/mrm.10371

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