An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: Development of a fluorescent lead(II) probe

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Abstract

(Chemical Equation Presented) Lighting up lead: A Pb2+- regulatory protein from Ralstonia metallidurans has been converted into a highly sensitive fluorescent Pb2+ probe (PbR691, turquoise circles in scheme). This fluorescent system reveals that the protein exhibits a surprisingly high binding selectivity towards Pb2+ ions over other metal ions. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

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Chen, P., Greenberg, B., Taghavi, S., Romano, C., Van Der Lelie, D., & He, C. (2005). An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: Development of a fluorescent lead(II) probe. Angewandte Chemie - International Edition, 44(18), 2715–2719. https://doi.org/10.1002/anie.200462443

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