Metal-free catalytic vicinal diamination of alkenes

Abstract

The development of an intramolecular vicinal diamination protocol using metalfree conditions is discussed. The reaction uses a bromide source to generate a Br(I) catalyst in situ from a benign terminal oxidant such as sodium chlorite. The reaction is of great scope and surpasses the transition-metal catalyses developed so far for these types of reactions. © 2013 IUPAC.