Avaliação clínica, laboratorial e radiográfica de Brasileiros com espondiloartropatias

Abstract

Objective: to evaluate disease manifestations of Brazilian patients with spondyloarthropathies. Methods: a group of 156 patients was studied in a descriptive evaluation the analysis of the association between clinical, laboratory and radiographic aspects and the presence of the HLA-B27 was done. Results: the following diseases were identified: ankylosing spondylitis (48.10%), undifferentiated spondyloarthropathy (20.51%), reactive arthritis (15.39%), psoriatic arthritis (14.10%) and inflammatory bowel disease arthropathy (1.92%). The HLA-B27 was identified in 53.85%. HLA-B27 presence was associated with clinical and/or radiographic findings of sacroiliac joints involvement (p=0.007; OR=3.13; CI 95% 1.38 to 7.06), with the presence of radiographic bilateral sacroiliitis ≥ grade II, bilateral (p=0.05; OR=2.85; IC 95% 1.02 to 8.04) and with male gender (p=<0.001; OR=3.00; CI 95% 1.83 to 4.92). On the other hand, negative HLA-B27 was significantly associated with the occurrence of balanitis during the course of the disease (p=0.03; OR=0.21; IC 95% 0.05 to 0.88). Conclusion: clinical, laboratory and radiographic manifestations were similar to those reported by other studies. The frequency of HLA-B27 was low when compared to other studies. A significant association was observed between the HLA-B27 and gender as well as compromised sacroiliac joints.