Research on clinical-paraclinical and evolutive aspects in patients with post spinal cord injury (SCI) statuses and Covid-19 – a systematic literature review

Abstract

The COVID-19 pandemic has generated a lot of interest among doctors as well as scientists around the world. Studies on the impact of the Covid-19 pandemic, including in people with post SCI sufferance, are ongoing, aiming to understand the pathophysiological mechanisms of SARS-CoV2 in target tissues, to optimize related methods of diagnosis and treatment in both, initial and later phases of the disease – e.g.: ”long Covid” status – and thus, to make a substantial contribution to the quality of life improvement of the affected patients. After using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (acronym PRISMA) method to quest for afferent knowledge, it resulted a quite small number (12) of articles, most of them indirectly approaching this topic. Therefore, is important to deepen this niche – which is scarcely approached – in order to find new therapeutic approaches able to combat COVID-19-associated to SCI manifestations – like, for instance, to check whether the principle of intermittent hypoxia treatment is effective and worth to be included in the rehabilitation treatment protocols – as neither an indubitable effective drug or vaccine, or respectively, cure for SCI, has been provided so far.