Engineering Biosensors and Biomedical Detection Devices from 3D-Printed Technology

Abstract

Limitation of 3D construction ability, complex preparation processes and developing customer demands have promoted people to find low-cost, rapid prototyping, and simple operation methods to produce novel functional devices in the near future. Among various techniques, 3D-printed technology is a promising candidate for the fabrication of biosensors and biomedical detection devices with a wide variety of potential applications. This review offers four important 3D printing techniques for biosensors and biomedical detection devices and their applications. The principle and printing process of 3D-printed technologies will be generalized, and the printing performance of many 3D printers will be compared. Despite the resolution restrictions of 3D-printed, these technologies have already shown promising applications in many biosensors and biomedical detection devices, such as 3D-printed microfluidic devices, 3D-printed optical devices, 3D-printed electrochemical devices, and 3D-printed integrated devices. Some of the most representative examples will also be discussed here, demonstrating that 3D-printed technology can rationally design biosensors and biomedical detection devices and achieve important applications in microfluidic, optical, electrochemical, and integrated devices.