Optimal sampling designs for accurate estimation of parasite clearance in the context of artemisinin resistance

  • Flegg J
  • Guerin P
  • Nosten F
  • et al.
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Abstract

Background The emergence of artemisinin resistance in South East Asia threatens the efficacy of artemisinin derivatives (AD). Since the pharmacodynamic hallmark of AD is rapid parasite clearance, the clinical phenotype of slow clearance characterises resistance. This ...

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Flegg, J. A., Guerin, P. J., Nosten, F., Dondorp, A. M., Fairhurst, R. M., Socheat, D., … Stepniewska, K. (2012). Optimal sampling designs for accurate estimation of parasite clearance in the context of artemisinin resistance. Malaria Journal, 11(S1). https://doi.org/10.1186/1475-2875-11-s1-p39

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