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Toponome Imaging System (TIS): imaging the proteome with functional resolution

  • Bode M
  • Krusche A
Nature Methods (2007) 4(1) iii-iv
DOI: 10.1038/nmeth998
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Abstract

The Toponome Imaging System (TIS) is the latest development in automated multidimensional fluorescence microscopy. It is capable of imaging over 100 different molecular components in a single cell or tissue section at continuous intensity levels for the first time. TIS directly addresses protein-network architecture and function in healthy and diseased statesa completely new dimension in the life sciences.

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Bode, M., & Krusche, A. (2007). Toponome Imaging System (TIS): imaging the proteome with functional resolution. Nature Methods, 4(1), iii–iv. https://doi.org/10.1038/nmeth998

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