Abstract
CRM1, chromosome region maintenance 1 protein also known as exportin-1 (XPO1), mediates the export out of the nucleus of cellular proteins with a leucine-rich nuclear export signal (NES, a short 8–15 amino acid hydrophobic motif), such as the HIV-1 Rev and the HTLV-1 Rex proteins, and the transport of small RNA cargoes. The gene for CRM1 is located on chromosome 2p15. CRM1 is widely conserved and is found in species ranging from candida, yeast, drosophila, xenopus, and mammals.
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CITATION STYLE
APA
Yedavalli, V. R. K. (2018). CRM1. In Encyclopedia of AIDS (pp. 395–397). Springer New York. https://doi.org/10.1007/978-1-4939-7101-5_78
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