Neutrophil lymphocyte ratio as useful predictive tool for glycaemic control in type 2 diabetes: Retrospective, single centre study in Turkey

Abstract

Objective: To evaluate the inflammatory cells in the complete blood count test and their relationship with the glycaemic control in type 2 diabetes patients. Methods: The retrospective clinical study was conducted at the Department of Family Medicine, Bezmialem Vakif University, Istanbul, Turkey, from January 2015 to June 2016, and comprised adult type 2 diabetes patients' data, like complete blood count and biochemical parameters. The data was stratified according to glycated haemoglobin levels; <7% in group 1, and >7% in group 2. Data was analysed using SPSS 21. Results: Of the 320 subjects, 172(54%) were in group 1 and 148(46%) in group 2. Overall, there were 106(33%) male and 214(67%) female subjects. The mean age of the sample was 53.6±11.9 years. White blood cell count, neutrophil count and neutrophil-lymphocyte ratios were significantly higher in group 2. Red blood cell count, mean platelet volume, fasting blood glucose, triglyceride, alanine aminotransferase levels were also significantly higher in group 2 (p <0.05). Conclusion: Simple complete blood count test can be used as a cost-effective tool to monitor glycaemic regulation in type 2 diabetes patients.