Phytoestrogens from Aspalathus linearis

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Abstract

From the leaves of Aspalathus linearis, 24 known compounds and a new one, aspalalinin (25), were isolated. The structures of the compounds were determined mainly based on spectral evidence. The absolute configuration of aspalalinin was presented on the basis of X-ray analysis. Each isolate was assessed for its estrogenic activity by an estrogen ELISA assay. Compounds 12, 15, and 24 showed the estrogenic activity. © 2006 Pharmaceutical Society of Japan.

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Shimamura, N., Miyase, T., Umehara, K., Warashina, T., & Fujii, S. (2006). Phytoestrogens from Aspalathus linearis. Biological and Pharmaceutical Bulletin, 29(6), 1271–1274. https://doi.org/10.1248/bpb.29.1271

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