Intracavernous injection of prostaglandin el in spinal cord injured patients with erectile dysfunction. A preliminary report

Abstract

Our experience with intracavernous injection of prostaglandin El in spinal cord injured patients with neurogenic erectile dysfunction included 15 men. They received testing dosage starting from 5 μg with increasing dosage (maximum 20 p, g) to achieve a rigid erection of Schramek’s grade 5 and lasting for at least 20 mm. All of them had achieved functional erection adequate for coitus after treatment except one patient who had been proved to have venogenic impotence. We found that intracavernous injection of prostaglandin El had significantly improved the erectile condition. No systemic side effect or any other complication was noted except that pain at the injection site was complained of m two patients with incomplete lesion. © 1995 International Medical Society of Paraplegia.