Antibiotic susceptibility of bacteria isolated from urinary cultures taken from children

Abstract

Objective: İn this study we aimed to determine antibiotic susceptibility of bacteria isolated from childhood urinary cultures in our hospital between 2009-2011.We thought that clinicians would make better decisions in selecting empirical antibiotics in urinary tract infections with every hospital publishing its own resistance profile. In addition, we observed changes in resistance ratios after training in rationalistic antibiotic useage and limited antibiogram notifications. Material and Methods: For this purpose, 19138 urinary cultures taken between 2009-2011 were analysed, retrospectively. The samples were implanted into blood agar (Premed, Türkiye) and EMB agar (Premed, Türkiye). Sensitivity tests were researched with the disk diffusion method in accordance with NCCLS criteria. Results: Reproduction was detected in 490 patients (10.2%) in 2009, in 377 patients (5.6%) in 2010, and in 905 patients (11.7%) in 2011. The most reproduced bacteria was Escherichia coli in all three years. Ampicilline, co-trimaksazole, ampicilline sulbactam and amoxicillin-klavunat were the antibiotics which have to be given attention in using empirical usage and have to be taken into account for their high resistance ratios. First and second generation cephalosporins are the antibiotics that could be used for the empirical treatments due to their low level of resistance ratios. Conclusion: Due to the fact that antibiotic resistance ratios vary from region to region, clinicians would have more chance in treatment if they take into consideration the selective region's data in writing empirical antibiotics in treatment of urinary tract infections. Besides,decline in resistance ratios after training in rationalistic antibiotic useage and limited antibiogram notifications is hopeful. The repetition of training courses periodically each year will be useful. © 2013 by Pediatric Infectious Diseases Society.