Nucleotide sequence of cDNA coding the mitochondrial precursor protein of the atpase inhibitor from humans

Abstract

Mitochondrial ATP synthase (F1Fo-ATPase) is regulated by an intrinsic ATPase inhibitor protein. In the present study, cDNA coding the human homolog of the inhibitor protein was isolated and sequenced. The deduced protein sequence shows that the protein was composed of 106 amino acids and had a molecular weight of 12248. The structural features of the protein show that the cDNA isolated in this study codes the human ATPase inhibitor. © 1999, Taylor & Francis Group, LLC. All rights reserved.