Biosynthesis and characterization of Saudi propolis-mediated silver nanoparticles and their biological properties

Abstract

The aim of this investigation was to synthesize propolis-mediated silver nanoparticles (Pro-AgNPs) and to test their biological activities in comparison with the raw materials (Saudi propolis). The chemical-physical characterization of the product showed that Pro-AgNPs were well synthesized. For the study of biological properties, aqueous and methanolic extracts were prepared from both propolis and Pro-AgNPs. Total polyphenol contents (TPCs) and antiradical activities showed their highest values in methanolic extracts, in particular in propolis extract. But, a higher TPC was found in Pro-AgNP aqueous extract as compared to propolis aqueous extract. It seems that Pro-AgNP synthesis helped extract more phenolic compounds with water. These compounds did not enhance antiradical activity in Pro-AgNP aqueous extract but increased its antibacterial activity.