Utility of Activated Nitriles in the Synthesis of Some New Heterocyclic Compounds

  • A. Fadda A
  • M. Mukhtar M
  • M. Refat H
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Abstract

New 4-(2-cyanoacetamido)benzoic acid (1) was utilized as key intermediate for the synthesis of some new thiazole, pyrazole, oxazole, pyrimidine, 1,3-dithiolane, thiophene, coumarin, oxazine and pyridazine derivatives. Newly synthesized compounds were characterized by elemental analyses and spectral data (IR, 1 H NMR and mass spectra).

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A. Fadda, A., M. Mukhtar, M., & M. Refat, H. (2012). Utility of Activated Nitriles in the Synthesis of Some New Heterocyclic Compounds. American Journal of Organic Chemistry, 2(2), 32–40. https://doi.org/10.5923/j.ajoc.20120202.06

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