Studies on the constituents of the leaves of Phellodendron japonicum MAXIM

Abstract

From the leaves of Phellodendron japonicum MAXIM. (Rutaceae), six new flavonoid glycosides (I-VI) were isolated, together with eight known compounds. The structures of I-VI were shown to be 8-prenyl-3,4',5-trihydroxyflavone 7-O-β-D-(6-O-malonyl) glucopyranoside, (2R, 3R)-8-prenyl-3,4',5-trihydroxyflavanone 7-O-β-D-(6-O-malonyl) glucopyranoside, 8-[(S)-2,3-dihydroxy-3-methylbutyl]-3,4',5-trihydroxyflavone 7-O-β-D-glucopyranoside, 8-[(R)-2,3-dihydroxy-3-methylbutyl]-3,4',5-trihydroxyflavone 7-O-β-D-glucopyranoside, (2R, 3R)-8-[(S)-2,3-dihydroxy-3-methylbutyl]-3,4',5-trihydroxyflavanone 7-O-β-D-glucopyranoside and (2R, 3R)-8-[(R)-2,3-dihydroxy-3-methylbutyl]-3,4',5-trihydroxyflavanone 7-O-β-D-glucopyranoside, respectively, on the basis of the chemical and spectral data.