HIV-1: Nature's master of disguise

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Abstract

HIV-1 readily mutates to escape the immune response, evolving in ways that allow it to persist in the host. New findings reveal that HIV-1 protects itself from antibodies by putting up a shield of constantly shifting sugar moieties. This shield may be contributing to the poor performance of candidate HIV-1 vaccines.

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Mascola, J. R., & Montefiori, D. C. (2003, April 1). HIV-1: Nature’s master of disguise. Nature Medicine. https://doi.org/10.1038/nm0403-393

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