Unravelling early sinus node dysfunction after paediatric cardiac surgery: A pre-existing arrhythmogenic substrate

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Abstract

Early postoperative sinus node dysfunction (SND) is common in paediatric patients undergoing surgical correction of congenital heart disease (CHD). At present, the pathophysiology of these arrhythmias is incompletely understood. In this case series, we present 3 paediatric patients in whom we performed intraoperative epicardial mapping and who developed early postoperative SND. All patients had either an inferior or multiple sinoatrial node (SAN) exit sites, in addition to extensive conduction disorders at superior and inferior right atrium. Our findings contribute to the hypothesis that pre-existing alterations in SAN exit sites in combination with atrial conduction disorders may predispose paediatric patients with CHD for early postoperative SND. Such insights into the development of arrhythmias are crucial as it may be the first step in identifying high-risk patients.

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Ramdat Misier, N. L., Taverne, Y. J. H. J., Van Schie, M. S., Kharbanda, R. K., Van Leeuwen, W. J., Kammeraad, J. A. E., … De Groot, N. M. S. (2023). Unravelling early sinus node dysfunction after paediatric cardiac surgery: A pre-existing arrhythmogenic substrate. Interdisciplinary Cardiovascular and Thoracic Surgery, 36(1). https://doi.org/10.1093/icvts/ivac262

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