Simple Syntheses of Two New Benzo-Fused Macrocycles Incorporating Chalcone Moiety

Abstract

Simple syntheses of the benzo-fused 26-membered macrocyclic bischalcone (19 E ,43 E )-2.11.27.36-tetroxaheptacyclo[44.4.0.0 4,9 .0 12,17 .0 21,26 .0 29,34 .0 37,42 ]pentaconta-1(46),4(9),5,7,12(17),13,15,19,21,23,25,29,31,33,37,39,41,43,47,49-icosaene-18,45-dione ( 3 ) and the benzo-fused 13-membered macrocyclic chalcone (19 E )-2.11-dioxatetracyclo[19.4.0.0 4,9 .0 12,17 ]pentacosa-1(25),4(9),5,7,12(17),13,15,19,21,23-decaen-18-one ( 5 ) using very common starting materials and reagents are described. The compounds are new and they have been characterized from their analytical and spectral data.