Methods for the synthesis of α-heterocyclic/heteroarylα-aminophosphonic acids and their esters

Abstract

This review describes a comprehensive account of methods which are commonly applied for the synthesis of α-heterocyclic/heteroaryl α-aminophosphonic acids and their esters. In the following order, protocols based on the methodologies listed below are discussed: (a) Pudovik reaction; (b) Kabachnik-Fields reaction and (c) Miscellaneous Methods.