Anti-tumor and anti-cancer activity test from Nabeez Ajwa Dates (Phoenix dactilifera L.) water

Abstract

Nabeez dates water is one of the fruits that is used as infused water. Dates contain flavonoids, phenols, alkaloids, and beta D-glucans which have anticancer and anti-tumor activity. Ajwa Dates have a higher phenol content than Sukkari Dates and Khalas Dates. Cancer is the number 5 deadliest disease in Indonesia and number 2 in the world after cardiovascular disease. The use of natural ingredients is an alternative for the treatment of this disease. One of the natural ingredients can be used is ajwa dates. The method of testing for anti-tumor and anti-cancer activity uses the Brine Shrimp Lethality Test (BSLT) method with shrimp larvae of Artemia salina leach as animals for testing. The results showed that the water of ajwa nabeez dates immersion for 24 hours, 48 hours, and 72 hours has the potential as anti-tumor and anti-cancer because it has an LC50 value of 676.39 ppm; 720.84 ppm; and 903.20 ppm. Phytochemical test results have shown positive samples containing tannins, phenolics, flavonoids, saponins, and alkaloids. The test results of FTIR spectophotometry resulted in the appearance of wave numbers indicating the presence of functional groups -OH, C-H, C = O, C-C (sp3), and C-O.©2020 JNSMR UIN Walisongo. All rights reserved.