Abstract
Ewing's sarcoma family tumors (ESFT) are characterized by specific chromosomal translocations, which give rise to EWS-ETS chimeric proteins. These aberrant transcription factors are the main pathogenic drivers of ESFT. Elucidation of the factors influencing EWS-ETS expression and/or activity will guide the development of novel therapeutic agents against this fatal disease. © 2011 David Herrero-Martin et al.
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APA
Herrero-Martin, D., Fourtouna, A., Niedan, S., Riedmann, L. T., Schwentner, R., & Aryee, D. N. T. (2011). Factors affecting EWS-FLI1 activity in Ewing’s sarcoma. Sarcoma. https://doi.org/10.1155/2011/352580
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