Development of calcium phosphate based bioceramics

Abstract

Two bioceramics (Ca-P-O glass and A-W glass ceramic) were produced using conventional methods of ceramic technology. X-ray powder diffraction patterns were used for identifying the phases and 3-point bend test was carried out for the determination of fracture strength of the bioceramics. Biocompatibility of both ceramics was evaluated using animal model experiments. Histological studies showed that A-W glass ceramic implanted in the tibia of rat formed an intimate contact with newly grown bone and provided enough strength to the bone to bear the animal weight. Implants made of Ca-P-O glass was almost fully resorbed and was replaced by new bone. The implants made of both the bioceramics were biocompatible and did not exhibit any kind of adverse effect to the surrounding tissues.