Study of the effects of the introduction of heparin on the mechanical properties of poly (glycolide-dl-lactide)

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Abstract

A technology has been developed for producing biodegradable films based on poly (glycolide-lactide) containing heparin. The obtained biodegradable films simulate the coatings of cava filters. The effect of the concentration of introduced heparin and the change in the molecular weight of poly (glycolide-lactide) on the strength and plastic properties, as well as on the thickness of the films obtained, is shown. The possibility of creating coatings with introduced heparin for cava filters with the required mechanical properties is shown.

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Baikin, A. S., Sergienko, K. V., Kaplan, M. A., Leonov, A. V., Kolmakova, A. A., Danilova, E. A., … Sevostyanov, M. A. (2019). Study of the effects of the introduction of heparin on the mechanical properties of poly (glycolide-dl-lactide). In IOP Conference Series: Materials Science and Engineering (Vol. 525). Institute of Physics Publishing. https://doi.org/10.1088/1757-899X/525/1/012099

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