Comment on “Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI”

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Abstract

The nuclear pregnane X receptor may not protect against ischemia/reperfusion-induced acute kidney injury in mice.

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Luan, Z., Ming, W., Zhang, C., Huo, X., Zheng, F., Zhang, X., & Guan, Y. (2021). Comment on “Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI.” Science Translational Medicine, 13(593). https://doi.org/10.1126/scitranslmed.abd0214

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