Combined Jellyfish Collagen Type II, Human Stem Cells and Tgf-β3 as a Therapeutic Implant for Cartilage Repair

Abstract

Background: The limitations associated to current therapies for articular cartilage repair led us to develop new strategies of applicable active therapeutic materials. Human mesenchymal stem cells from bone marrow are promising relevant cell sources for cell therapy and regenerative medicine, in particular for cartilage repair. Recently, a new source of non-mammalian collagen type II emerged and represents a promising tool for cartilage tissue engineering.