Antihypertensive Action of the Orally Administered Protease Hydrolysates of Chum Salmon Head and Their Angiotensin I-Converting Enzyme Inhibitory Peptides.

Tomoki OHTA; Atsuko IWASHITA; Shigefumi SASAKI; Yukio KAWAMURA

Journal ArticleOPEN ACCESS

Antihypertensive Action of the Orally Administered Protease Hydrolysates of Chum Salmon Head and Their Angiotensin I-Converting Enzyme Inhibitory Peptides.

OHTA T
IWASHITA A
SASAKI S
et al.

Food Science and Technology International, Tokyo (1997) 3(4) 339-343

DOI: 10.3136/fsti9596t9798.3.339

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Abstract

The antihypertensive action of protease hydrolysates derived from chum salmon head was investigated by oral administration to spontaneously hypertensive rats (SHR), and the angiotensin I-converting enzyme (ACE) LEC 3.4.15.1] inhibitory peptides were isolated from them. Hydrolysates by Biopurase SP-10 showed the highest ACE inhibitory activity in vitro. The systolic blood pressure of SHR treated with the hydrolysates orally decreased from 200.6i5.0 to 177.2i9.9 (0.05

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OHTA, T., IWASHITA, A., SASAKI, S., & KAWAMURA, Y. (1997). Antihypertensive Action of the Orally Administered Protease Hydrolysates of Chum Salmon Head and Their Angiotensin I-Converting Enzyme Inhibitory Peptides. Food Science and Technology International, Tokyo, 3(4), 339–343. https://doi.org/10.3136/fsti9596t9798.3.339

Antihypertensive Action of the Orally Administered Protease Hydrolysates of Chum Salmon Head and Their Angiotensin I-Converting Enzyme Inhibitory Peptides.

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