Calcium hydroxylapatite for collagen biostimulation in the neck

Abstract

Calcium hydroxylapatite (CaHA) is intended to volumize and to stimulate neocollagenesis, and it is effective to treat facial and extrafacial regions. This study was conducted with 5 patients with an aged cervical region. Photographs and biopsies were performed before treatment and 5 months later. The filler was injected into the subdermal plane of the anterior cervical region. Photos were analyzed by 10 dermatologists and the patient satisfaction was questioned. According to the specialists there was a reduction in aging (p = 0.001), although there was no difference between the patient satisfaction scores (p = 0.576). Histology showed that the collagen fibers were thick and irregular in both pre and post treatment, but in most cases, we noticed more compact collagen and elastic fibers afterwards, with new areas of horizontalization. CaHA is effective in improving the appearance and the biostimulation of collagen in the cervical region.