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Porcine cancer models for translational oncology

Molecular and Cellular Oncology (2014) 1(4)
DOI: 10.4161/23723548.2014.969626
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Abstract

Large-animal cancer models are needed to advance the development of innovative and clinically applicable tumor diagnostic, therapeutic, and monitoring technologies. We developed a genetically modified porcine model of cancer based on a TP53 mutation, and established its utility for tracking tumorigenesis in vivo through non-invasive clinical imaging approaches.

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Sieren, J. C., Quelle, D., Meyerholz, D. K., & Rogers, C. S. (2014). Porcine cancer models for translational oncology. Molecular and Cellular Oncology, 1(4). https://doi.org/10.4161/23723548.2014.969626

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