The Effect of Cinnamon Bark Extract (Cinnamomum burmannii) on Blood Glucose Levels in Hyperglycemic Rats

Abstract

Diabetes mellitus is a disease in the form of a metabolic disorder characterized by blood sugar levels that exceed normal limits. In diabetes, there is an increase in blood sugar (hyperglycemia) which occurs due to abnormalities in insulin secretion by the pancreas. The cinnamon bark plant (Cinnamomum burmannii) is one of the plants that contains antidiabetics. The aim of this research is to determine the effect of cinnamon bark extract on the blood glucose levels of hyperglycemic rats. This research is an experimental research with a Post Test-Only Control Group design using 30 rats divided into five groups, namely K(-) distilled water, K(+) Alloxan induction, then continued administration of cinnamon bark extract (Cinnamomum burmannii) P1 (Dose 100 mg/kgBW), P2 (Dose 200 mg/kgBW) and P3 (Dose 300 mg/kgBW) for 30 days. Checking blood glucose levels using the enzymatic glucose method. The results showed that cinnamon bark extract (Cinnamomum burmannii) had an effect on reducing blood glucose levels (p<0.05). Keywords: Hyperglycemic, Cinnamon Bark Extract, Antidiabetic